CCSN HPEN Scientific Publications


Where available, click on PDF to download a copy of the article. Note: All articles are the sole copyright of the respective publishers. Materials are provided for educational use only. Downloading of materials constitutes an agreement that the materials are for your personal educational use only.

Google Scholar Analytics: Click Here


1.  Cacioppo, S. (2017). High-performance electrophysiological microsegmentation and brain source localization. In J. T. Cacioppo, L. Tassinary, & G. Berntson (Eds.), Handbook of psychophysiology (4th ed.) Cambridge: Cambridge University Press.

2.  Cacioppo, S. (in press). Neuroscience of Salutary Close Relationships. Book chapter. In A. L. Vangelisti, & D. Perlman (Eds.), Handbook of Personal Relationships, Cambridge: Cambridge University Press.

3. Cacioppo, J.T., Cacioppo, S.,  Petty, R. E. (2017) The neuroscience of persuasion: A review with an emphasis on issues and opportunities. Social Neuroscience, 1-44. Doi:

4. Layden, E. A., Cacioppo, J. T., Cacioppo, S, Cappa, S. F., Dodich, A., Falini, A., & Canessa, N. (2017) Perceived social isolation is associated with altered functional connectivity in neural networks associated with tonic alertness and executive control. Neuroimage58-73. doi: 10.1016/j.neuroimage.2016.09.050. [Epub ahead of print] PubMed PMID: 27664824. 


1.    Cacioppo, S., Weiss, R.M., & Cacioppo, J.T. (2016) Dynamic spatiotemporal brain analyses of the visual checkerboard task: Similarities and differences between passive and active viewing conditions. Psychophysiology,  53(10):1496-506. doi: 10.1111/psyp.12723. Epub 2016 Jul 9. PubMed PMID: 27393016.

2.   Cacioppo, S. (2016). What happens in your brain during mental dissociation? A quest towards neural markers of a unified sense of self. Current Behavioral Neuroscience Reports, 3, 1-9. Doi: 10.1007/s40473-016-0063-8. 

3. Cacioppo, S. (2016). Neural markers of interpersonal attraction: A possible new direction for couple’s therapy. Emotion Researcher, ISRE’s Sourcebook for Research on Emotion and Affect. Andrea Scarantino (Ed). 

4.   Cacioppo, S., Bangee, M., Balogh, S., Cardenas-Iniguez, C., Qualter, P., & Cacioppo, J. T. (2016). Loneliness and implicit attention to social threat: A high performance electrical neuroimaging study. Cognitive Neuroscience, 7, 138-159. doi: 10.1080/17588928.2015.1070136.

5. Cacioppo, S. & Cacioppo, J. T. (2016). Cognizance of the Neuroimaging Methods for Studying the Social Brains. In: Shared representations: Sensorimotor foundations of social life. Sukhvinder s. Obhi & Emily S. Cross (Editors). Cambridge University Press: Cambridge, U.K. (pp. 59-85)

6. Cacioppo, J.T., Cacioppo, S.,  Adler, A., Lester, P.B., McGurk, D., Thomas, J.L., & Chen, HY. (2016). The cultural context of loneliness: Risk factors in active duty soldiers. Journal of Social and Clinical Psychology, 35, 865-882. 

7. Necka, L. Cacioppo, S., Norman, G. J., Cacioppo, J.T. (2016). Measuring the prevalence of problematic respondent behaviors among MTurk, campus, and community. PLoS One, 11(6):e0157732. doi: 10.1371/journal.pone.0157732. 

8. Van Roekel, E., Verhagen, M., Engels, R. C. M. E., Scholte, R. H. J., Cacioppo, S.,  & Cacioppo, J. T. (2016) Trait and State Levels of Loneliness: Examining Developmental and Cultural Differences in Adolescence. Journal of Clinical Child and Adolescent Psychology. May 18, 1-12. [Epub ahead of print] PubMed PMID: 27191708. 

9. Wang, Y. W., Son, J., Guo, F., Zang, Z., Yuan, S., & Cacioppo, S.  (2016). Spatiotemporal brain dynamics of empathy for pain and happiness in friendship. Frontiers in Behavioral Neuroscience.


  1. Cacioppo, S., & Cacioppo, J. T. (2015). Dynamic spatiotemporal brain analyses using high-performance electrical neuroimaging, Part II: A Step-by-Step Tutorial. Journal of Neuroscience Methods, 256: 184-197. pii: S0165-0270(15)00337-4. Doi: 10.1016/j.jneumeth.2015.09.004. PDF
  2. Cacioppo, S., Balogh, S., & Cacioppo, J.T. (2015). Implicit attention to negative social, in contrast to nonsocial, words in the Stroop task differs between individuals high and low in loneliness: Evidence from event-related brain microstates. Cortex, 70,  213-233. doi: 10.1016/j.cortex.2015.05.032. PDF
  3. Cacioppo, S., & Cacioppo, J. T. (2015) Why allopregnanolone may alleviate loneliness?  Medical Hypotheses. Doi: 10.1016/j.mehy.2015.09.004.  PDF
  4. Cacioppo, S. & Cacioppo, J.T. (2015). Demystifying the neuroscience of love. Emotion Review. Emotion Review, doi: 10.1177/1754073915594432. PDF
  5. Cacioppo, S., Grippo, A. J., London, S., Goossens, L, & Cacioppo, J. T. (2015). Loneliness: Clinical Import and Interventions. Perspectives on Psychological Science, 10, 238-249. 
  6. Cacioppo, J.T., Cacioppo, S., Capitanio, J. P., & Cole, S. W. (2015). The neuroendocrinology of social isolation. Annual Review of Psychology, 66, 9.1-9.35. [Trilogy on Human and Animal Research on Loneliness and Social Isolation; Part II]
  7. Cacioppo, J. T., Cacioppo, S., Cole, S. W., Capitanio, J. P, Goossens, & Boomsma, D. I. (2015). Loneliness Across Phylogeny and a Call for Comparative Studies and Animal Models. Perspectives on Psychological Science, 10, 202-212[Trilogy on Human and Animal Research on Loneliness and Social Isolation; Part III]
  8. Cacioppo, J.T., Adler, A. B., Lester, P. B., McGurck, D., Thomas, J. L., Chen, H. Y., & Cacioppo, S. (2015). Building Social Resilience in Soldiers: A Double Dissociative Randomized Controlled Study. Journal of Personality and Social Psychology, 109: 90-105.  
  9. Necka, E. A., Cacioppo, S., Cacioppo, J.T. (2015). Social Neuroscience of the 21st Century. The International Encyclopedia of Social and Behavioral Sciences. 
  10. Goossens, L., van Roekel, E., Verghaen, M., Cacioppo, J. T., Cacioppo, S., Maes, M., & Boomsma, D. I. (2015). The genetics of loneliness: Linking evolutionary theory to genome-wide genetics, epigenetics, and social science. Perspectives on Psychological Science, 10, 213-226.


  1. Cacioppo, S., Weiss, R. M. Runesha, H. B., & Cacioppo, J. T. (2014). Dynamic Spatiotemporal Brain Analyses using High Performance Electrical NeuroImaging: Theoretical Framework and Validation. Journal of Neuroscience Methods, 238, 11-34. doi: 10.1016/j.jneumeth.2014.09.009. PDF
  2. Wang, Y., Huang, L., Zhang, W., Zhang, Z., & Cacioppo, S. (2014). Spatio-temporal dynamics of kind versus hostile intentions in the human brain: An electrical neuroimaging study. Social Neuroscience, Dec 17: 1-15. PDF
  3. Cacioppo, S., Fontang, F., Patel, N., Decety, J., Monteleone, G., & Cacioppo, J. T. (2014). Intention understanding over T: A neuroimaging study on shared representation and tennis return predictions. Frontiers in Human Neuroscience. doi: 10.3389/fnhum.2014.00781. PDF
  4. Cacioppo, S., Zhou, H., Monteleone, G., Majka, E. A., Quinn, K. A., Ball, A. B., Norman, G. J., Semin, G. R., & Cacioppo, J. T. (2014). You are in sync with me: Neural correlates of interpersonal synchrony with a partner. Neuroscience, 277, 842-858.   doi: 10.1016/j.neuroscience.2014.07.051. July 31.  PDF
  5. Bolmont, M., Cacioppo, J.T., & Cacioppo, S. (2014). Love is in the gaze: An eye-tracking study of love and sexual desire. Psychological Science. July 16. pii: 0956797614539706.  PDF
  6. Cacioppo, S., Capitanio, J. P., & Cacioppo, J. T. (2014). Toward a neurology of loneliness. Psychological Bulletin, 140: 1464-1504 [Trilogy on Human and Animal Research on Loneliness and Social Isolation; Part I]
  7. Cacioppo, J.T., & Cacioppo, S.  (2014). Social isolation. In Conferência do XXXIV Congresso Interamericano de Psicologia, João Alchieri & Juliana Barreiros Porto (Eds), SIP.
  8. Cacioppo, J. T., Cacioppo, S., Dulawa, S., Palmer, A. (2014)Social neuroscience and its potential contribution to psychiatry. World Psychiatry, 13, 131-139. PDF
  9. Cacioppo, J. T., & Cacioppo, S. (2014).  Social relationships and health: The toxic effects of perceived social isolation.  Social and Personality Psychology Compass, 8, 58-72. PDF
  10. Cacioppo, J. T., Cacioppo, S., & Boomsma, D.I. (2014). Evolutionary mechanisms for loneliness. Cognition and Emotion, 28, 3-21. doi:10.1080/02699931.2013.837379. PDF
  11. Dai, J.Q, Zhai, H., Wu, H. Yang, S., Cacioppo, J.T., Cacioppo, S., & Luo, Y.J. (2014). Maternal face processing in Mosuo pre-school children. Biological Psychology, 99, 69-76. doi:10.1016/j.biopsycho.2014.03.001. PDF
  12. Wu, H, Chen, C., Cheng, D., Yang, S. Huang, R. Cacioppo, S., & Luo, Y. (2014).  The mediation effect of menstrual phase on negative emotion processing: Evidence from N2. Social Neuroscience. doi. 10.1080/17470919.2014.886617. PDF 
  13. Cacioppo, J. T., Cacioppo, S., Gollan, J. K. (2014)The Negativity Bias: Conceptualization, Quantification, and Individual Differences. Behavioral and Brain Sciences, 37(3): 309-310. PDF


  1. Cacioppo S., Couto B., Bolmont M., Sedeno L., Frum C., Lewis, J. W., Manes F., Ibanez  A., Cacioppo, J. T. (2013) Selective decision-making deficit in love following damage to the anterior insula. Current Trends in Neurology, 7, 15-19. PDF
  2. Cacioppo, J.T., Cacioppo, S., & Cole, S.W. (2013) Social neuroscience and social genomics: The emergence of multi-level integrative analyses. Int. J. Psychol. Res. 6, 1-6. PDF.
  3. Cacioppo, S., & Cacioppo, J.T. (2013) Do you feel lonely? You are not alone: Lessons from social neuroscience. Frontiers in Neuroscience for Young Minds, November 9. PDF
  4. Cacioppo, J. T. & Cacioppo, S. (2013) Social Neuroscience. Perspectives on Psychological Science 8(6), 667-669. PDF
  5. Radman, N., Cacioppo, S., Spierer, L., Schmidlin, E., Mayer, E., Annoni, J.M. (2013) Posterior SMA Syndrome following subcortical stroke: contralateral akinesia reversed by visual feedback. Neuropsychologia, 51, 2605-2610. doi: 10.1016/j.neuropsychologia.2013.08.004. PDF
  6. Cacioppo, S., & Cacioppo, J.T. (2013). Lust for life. Scientific American Mind, 24, 56-63[Preview]
  7. Cacioppo, S., Frum C., Asp E., Weiss R. M., Lewis J. W., Cacioppo, J. T. (2013) A quantitative meta-analysis of functional imaging studies of social rejection. Scientific Reports, 3, 2027. doi: 10.1038/srep02027. PDF
  8. Cacioppo J. T., Cacioppo, S., Gonzaga, G.C., Ogburn, E.L., VanderWeele, T.J. (2013) Marital Satisfaction and Break-ups Differ across On-line and Off-line meeting venues. Proceedings of the National Academy of Sciences of the United States of America, 110, 10135-10140. doi: 10.1073/pnas.1222447110. PDF.
  9. Cacioppo S, Bianchi-Demicheli, F., Bischof P., DeZiegler, D., Michel, C.M., Landis (2013) Hemispheric Specialization Varies with EEG Brain Resting States and Phase of Menstrual Cycle. PLoS ONE 8, e63196. PDF.
  10. Cacioppo, J.T. & Cacioppo, S. (2013). Older adults reporting social isolation or loneliness show poorer cognitive function four years later. Evidence-Based Nursing, BMJ. Jun 8. PDF.
  11. Juan, E., Frum, C., Bianchi-Demicheli, F., Wang, Y., Lewis J. W., Cacioppo, S. (2013). Beyond human intentions and emotions. Frontiers in Human Neuroscience, 7: 99. doi: 10.3389/fnhum.2013.00099 PDF.
  12. Cacioppo, J.T. & Cacioppo, S. (2013). Minimal replicability, generalizability, and scientific advances in psychological science. European Journal of Personality, 27: 121-122. PDF.
  13. Cacioppo, S. & Hatfield, E. (2013). From desire to love: New advances from social neuroscience.  In L. Bormans (Eds). “The World Book of Love" (pp. 116-119). Tielt, Belgium: Lannoo Publishers. PDF.


  1. Cacioppo, J.T. & Cacioppo, S. (2012). Metrics of Scholarly Impact. Measurement: Interdisciplinary research and perspectives, 10, 154-156. PDF
  2. Cacioppo, S., Grafton, S.T., Bianchi-Demicheli, F. (2012). The speed of passionate love, as a subliminal prime: A high-density electrical neuroimaging study. NeuroQuantology, 10, 715-724. PDF
  3. Decety, J. & Cacioppo, S. (2012). The speed of morality: a high-density electrical neuroimaging  study. Journal of Neurophysiology 108, 3068-72. PDF
  4. Cacioppo, S. & Cacioppo, J, T. (2012). Decoding the invisible forces of social connections. Front. Integr. Neurosci. 6, Article 51, 1-7. PDF
  5. Cacioppo, J.T. & Cacioppo, S. (2012). The phenotype of loneliness. European Journal of Developmental Psychology. European Journal of Developmental Psychology, 9,  446-452(7). PDF
  6. Cacioppo, S., Bianchi-Demicheli, F., Hatfield, E., Rapson, R.L. (2012). Social Neuroscience of love, Clinical NeuroPsychiatry. 9, 3-13. PDF
  7. Cacioppo, S., Bianchi-Demicheli, F., Frum, C., Pfaus, J., Lewis, J.W. (2012). The common neural bases between sexual desire and love: a multilevel kernel density fMRI analysis. Journal of Sexual Medicine, 9, 1048-1054. doi: 10.1111/j.1743-6109.2012.02651.x. PDF



  • Cacioppo, J. T. & Ortigue, S. (2011). Social Neuroscience: how a multidisciplinary field is uncovering the biology of human interactions. Cerebrum 12, 1-7. PDF
  • Ortigue, S. & Bianchi-Demicheli, F. (2011). Intention, false beliefs, and delusional jealousy: Insights into the right hemisphere from neurological patients and neuroimaging studies. Medical Science Monitor, 17, RA1-11. PDF
  • Bianchi-Demicheli, F., Cojan, Y., Waber, L., Recordon, N., Vuilleumier, P., Ortigue, S. (2011). Neural bases of hypoactive sexual desire disorder in women: an event-related fMRI study. Journal of Sexual Medicine, 8,  2546-2559. PDF


  • Ortigue, S., Patel, N., Bianchi-Demicheli, F., Grafton, S.T. (2010). Implicit priming of embodied cognition on human motor intention understanding in dyads in love. Journal of Social and Personal Relationships, 27, 1001-1015. PDF
  • Ortigue, S., Bianchi-Demicheli, F., Patel, N., Frum, C., Lewis, J. (2010). Neuroimaging of love: fMRI meta-analysis evidence towards new perspectives in sexual medicine. Journal of Sexual Medicine, 7,  3541-3552. PDF
  • Ortigue, S., Sinigaglia, C., Rizzolatti, G., Grafton, S.T. (2010). Understanding actions of others: the electrodynamics of the left and right hemispheres. A high-density EEG neuroimaging study. PLOS ONE, 5:e12160. PDF
  • Brown, K., Ortigue, S., Grafton, S.T., Carlson, J. (2010). Improving human brain mapping via joint inversion of brain electrodynamics and the BOLD signal. NeuroImage 49, 2401–2415. PDF
  • Bianchi-Demicheli, F., Rollini, C., Lovblad, K., Ortigue, S. (2010). “Sleeping beauty paraphilia”: Deviant desire in the context of bodily self-image disturbance in a patient with a fronto-parietal traumatic brain injury. Medical Science Monitor 16, CS15-7. PDF
  • Ortigue, S. & Kreiman, G. (2010). From inner perception to embodied cognition: a window to consciousness. Psyche Vol 16, No 1. PDF
  • Kreiman, G. & Ortigue, S. (2010). Past, Present, and Future of Scientific Research on Consciousness. Psyche Vol 16, No 2. PDF


  • Brookings, T., Ortigue, S., Grafton, S., Carlson, J. (2009). Using ICA and realistic BOLD models to obtain joint EEG/fMRI solutions to the problem of source localization. NeuroImage 44, 411-420. PDF
  • Ortigue, S., Patel, N., Bianchi-Demicheli, F. (2009). New EEG neuroimaging methods of analyzing brain activity applicable to the study of human sexual response. Journal of Sexual Medicine 6, 1830-45. PDF
  • Ortigue, S., King, D., Gazzaniga, M., Miller, M., Grafton, S.T. (2009). Right hemisphere dominance for understanding intentions of others: Evidence from a split-brain patient. BMJ case reports [doi:10.1136/bcr.07.2008.0593]. PDF
  • Ortigue, S., Thompson, J., Parasuraman, R., Grafton, S.T. (2009). Spatio-temporal dynamics of human intention understanding: A combined EEG/fMRI repetition suppression paradigm. PLOS ONE 4(9):e6962. PDF
  • Kreiman, G. & Ortigue. S. (2009). (To be) conscious or unconscious: that is the question. Psyche Vol 15 , No 2. PDF


  • Ortigue, S. & Bianchi-Demicheli, F. (2008). Why is your spouse so predictable? Connecting mirror neuron system and self-expansion model of love. Medical Hypotheses 71, 941-4. PDF
  • Ortigue, S. & Bianchi-Demicheli, F. (2008). The chronoarchitecture of human sexual desire: a high-density electrical mapping study. NeuroImage 43, 337-345. PDF
  • Tunik, E., Ortigue, S., Adamovich, S., Grafton, S. (2008). Differential recruitment of anterior intraparietal sulcus and superior parietal lobule during visually guided grasping revealed by electrical neuroimaging. Journal of Neuroscience 28, 13615-13620. PDF


  • Ortigue, S., Bianchi-Demicheli, F., Hamilton, A.F., Grafton, S.T. (2007). The neural basis of  love as a subliminal prime: an event-related fMRI study. Journal of Cognitive Neuroscience 19, 1218-1230. PDF
  • Ortigue, S., Grafton, S.T., Bianchi-Demicheli, F. (2007). Correlation between insula activation and self-reported quality of orgasm in women. NeuroImage 37, 551-560. PDF
  • Bianchi-Demicheli, F. & Ortigue, S. (2007). Toward an understanding of the cerebral substrates of woman’s orgasm. Neuropsychologia 45, 2645-2659. PDF


  • Ortigue, S., Megevand, P., Perren, F., Landis, T., Blanke, O. (2006). Double dissociation between representational personal and extrapersonal neglect. Neurology 66, 1414-1417.
  • Arzy, S., Seeck, M., Ortigue, S., Spinelli, L., Blanke, O. (2006). Induction of an illusory shadow person. Nature 443, 287. PDF


  • Ortigue, S., Thut, G., Landis, T., Michel, C. M. (2005). Time-resolved sex differences in language lateralization. Brain 128, E28. PDF
  • Mohr, C., Michel, C. M., Lantz, G., Ortigue, S., Viaud-Delmon, I., Landis, T. (2005). Brain state-dependent functional hemispheric specialization in men but not in women. Cerebral Cortex 15, 1451-1458. PDF
  • Ortigue, S., Jabaudon, D., Landis, T., Michel, C.M., Maravita, A., Blanke, O. (2005). Preattentive interference between touch and audition: a case study on multisensory alloesthesia. Neuroreport 16, 865-868. PDF


  • Ortigue, S., Michel, C. M., Murray, M. M., Mohr, C., Carbonnel, S., Landis, T. (2004). Electrical neuroimaging reveals early generator modulation to emotional words. NeuroImage 21, 1242-1251. PDF
  • Murray, M. M., Michel, C. M., Grave de Peralta, R., Ortigue, S., Brunet, D., Gonzalez Andino, S., Schnider, A. (2004). Rapid discrimination of visual and multisensory memories revealed by electrical neuroimaging. NeuroImage 21, 125-135. PDF
  • Vuilleumier, P., Ortigue, S., Brugger, P. (2004). The number space and neglect. Cortex, 40, 399-410.
  • Ortigue, S., Landis, T., Michel, C. M., Blanke, J., Martory, M. D., Blanke, O. (2004). Letters lost in space : hemispace dependent handwriting errors. Neuroreport 15, 2545-2548. PDF


  • Blanke, O., Ortigue, S., Landis, T. (2003). Colour neglect in an artist. The Lancet 361, 264. PDF
  • Ortigue, S., Viaud-Delmon, I., Michel, C.M., Blanke, O., Annoni, J.M., Pegna, A., Mayer, E., Spinelli, L., Landis, T. (2003). Pure imagery hemi-neglect of far space. Neurology, 60, 2000-2002. PDF
  • Blanke, O., Ortigue, S., Coeytaux, A., Martory, M. D., Landis, T. (2003). Hearing of a presence. Neurocase 9, 329-339. PDF


  • Blanke, O., Ortigue, S., Landis, T., Seeck, M. (2002). Stimulating illusory own-body perceptions. Nature, 419, 269-270. PDF


  • Ortigue, S., Viaud-Delmon, I., Annoni, J. M., Landis, T., Michel, C. M., Blanke, O., Vuilleumier, P., Mayer, E. (2001). Pure representational neglect after right thalamic lesion. Annals of Neurology 50, 401-404. PDF


How do I cite HPEN in my scientific publications and talks?

Citing HPEN in your scientific publications and talks will help CCSN HPEN demonstrate the role of high performance electrical neuroimaging resources and support staff in research at UChicago. 

Reference the CCSN HPEN as “The University of Chicago CCSN High Performance Electrical NeuroImaging Laboratory” in citations. Acceptable example citations are below.

  • This work was completed in part with resources provided by the University of Chicago CCSN High Performance Electrical NeuroImaging Laboratory.
  • We are grateful for the support of the University of Chicago CCSN HPEN Laboratory for assistance with the electrical neuroimaging recordings carried out in this work.
  • We acknowledge the University of Chicago CCSN High Performance Electrical NeuroImaging Laboratory for support of this work.

Please send an email to with the title, journal, or conference to let us know where a scientific presentation was given that made use of CCSN HPEN resources.